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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM3
All Species:
27.58
Human Site:
S535
Identified Species:
43.33
UniProt:
P25205
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25205
NP_002379.2
808
90981
S535
A
T
D
D
P
N
F
S
Q
E
D
Q
Q
D
T
Chimpanzee
Pan troglodytes
XP_001151750
808
90957
S535
A
T
D
D
P
N
F
S
Q
E
D
Q
Q
D
T
Rhesus Macaque
Macaca mulatta
XP_001106966
808
90990
S535
A
T
D
D
P
N
F
S
Q
E
D
Q
Q
D
T
Dog
Lupus familis
XP_538960
916
102667
N643
A
T
D
D
P
D
F
N
Q
E
D
Q
Q
D
T
Cat
Felis silvestris
Mouse
Mus musculus
P25206
812
91528
T535
A
T
D
D
P
D
F
T
Q
D
D
Q
Q
D
T
Rat
Rattus norvegicus
XP_001070728
813
91641
T535
A
T
D
D
P
D
F
T
Q
D
D
Q
Q
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
A536
A
T
D
D
P
D
F
A
Q
E
E
E
Q
E
L
Frog
Xenopus laevis
Q7ZXZ0
806
90528
T535
A
T
E
D
P
N
V
T
S
E
E
Q
Q
E
L
Zebra Danio
Brachydanio rerio
NP_997732
807
90502
T534
A
T
E
D
P
D
A
T
Q
E
E
E
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511048
819
90900
S529
S
L
S
F
V
S
S
S
E
E
K
K
D
T
E
Honey Bee
Apis mellifera
XP_625020
811
91329
L533
T
K
N
P
D
Q
I
L
F
E
E
T
E
T
Q
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
G492
A
A
A
N
S
V
Y
G
R
W
D
E
S
R
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
R498
Q
I
S
E
H
V
A
R
M
H
R
Y
C
T
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
G508
R
G
E
A
G
P
D
G
S
L
P
Y
A
R
E
Baker's Yeast
Sacchar. cerevisiae
P24279
971
107499
D619
N
E
G
E
D
D
E
D
H
V
F
E
K
F
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
86
N.A.
92.9
93.3
N.A.
N.A.
81.4
80.1
75.9
N.A.
62.5
62.7
30.8
N.A.
Protein Similarity:
100
99.8
100
87.2
N.A.
96.6
97
N.A.
N.A.
92
90.7
88.1
N.A.
80
78.6
49.5
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
60
53.3
40
N.A.
13.3
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
80
86.6
N.A.
40
26.6
40
N.A.
Percent
Protein Identity:
N.A.
47.6
N.A.
49.3
39.8
N.A.
Protein Similarity:
N.A.
66
N.A.
68.1
54.7
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
7
7
7
0
0
14
7
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
47
60
14
40
7
7
0
14
47
0
7
40
7
% D
% Glu:
0
7
20
14
0
0
7
0
7
60
27
27
14
20
14
% E
% Phe:
0
0
0
7
0
0
47
0
7
0
7
0
0
7
0
% F
% Gly:
0
7
7
0
7
0
0
14
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
7
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
0
0
0
0
0
7
7
7
0
0
% K
% Leu:
0
7
0
0
0
0
0
7
0
7
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
0
7
7
0
27
0
7
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
7
60
7
0
0
0
0
7
0
0
0
0
% P
% Gln:
7
0
0
0
0
7
0
0
54
0
0
47
54
0
7
% Q
% Arg:
7
0
0
0
0
0
0
7
7
0
7
0
0
14
0
% R
% Ser:
7
0
14
0
7
7
7
27
14
0
0
0
7
0
0
% S
% Thr:
7
60
0
0
0
0
0
27
0
0
0
7
0
20
40
% T
% Val:
0
0
0
0
7
14
7
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _